Vitamin K2, collagen-calcium combo closing awareness, evidence gaps in bone health

While the combination of calcium and vitamin D is the best known duo in bone health, other ingredients that stories to tell are closing the gap both in terms of clinical evidence and public acceptance, suppliers say.

Take vitamin K2. Evidence has shown that an adequate level of this vitamin, which refers to a couple of different metabolized forms of vitamin K, is critical in regulating the mobility of calcium in and out of the bones. Several firms, including NattoPharma and its Norwegian rival Kappa Bioscience, supply different types of the more efficacious menaquinone 7 form of the vitamin. 

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New RCT: KoACT® Beats Calcium and Vitamin D for Optimal Bone Strength

Long-term study is first to show that a unique patented calcium collagen product, KoACT, reduces bone loss and builds new bone in post-menopausal women

City of Industry, CA – October 28, 2014 – A new randomized controlled trial (RCT) of post-menopausal women demonstrates that a proprietary blend of collagen and calcium, KoACT®, was far superior to calcium and vitamin D in slowing down the leaching of calcium from bones and rebuilding new bone strength. An Abstract of the article appears on PubMed at:, ahead of print in The Journal of Medicinal Food.

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New Survey: Post Menopausal Women “Get” Bone Health Risks Bus Less Than Half Taking Supplements

Lack of understanding of new science key factor in low awareness

City of Industry, CA – October 6, 2014 – Make no bones about it; post-menopausal women are well aware of the risks of brittle bones and fractures; however, a national survey of women taken for AIDP, Inc., the supplier of KoACT®, a patented combination of collagen and calcium, found that almost half (49%) are not taking any bone health supplement to address this major health issue. And, even fewer are not aware of the newest science supporting that a calcium-collagen combination is optimal for bone health.

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AIDP announces published initial results of U.S. clinical trial on the effects of KoACT® on bone strength

Subjects treated with KoACT® showed evidence of bone reversal properties.

City of Industry, Calif. (February 19, 2013) – AIDP has announced three-month study results of a double-blind, placebo-controlled U.S.-based clinical trial of KoACT® at Florida State University in Tallahassee, Florida, led by Dr. Bahram Arjmandi, Margaret A. Sitton professor and chair, department of nutrition, food & exercise sciences and director for the Center for Advancing Exercise and Nutrition Research on Aging.

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